Across TCGA patient cohorts, ARHGAP30 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP30-associated genes across cancer lineages are 4E-BP1, 14-3-3_beta, and ATM. Each is linked with ARHGAP30 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARHGAP30-to-partner and partner-to-ARHGAP30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP30→partner) and Y-score (partner→ARHGAP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	4E-BP1 →	+0.332	+2.502	<.001	.001	3	4
UCEC	14-3-3_beta →	-0.083	-1.651	.004	.019	3	3
UCEC	ATM →	-0.376	-1.794	.004	.024	3	3
COAD	Caspase-7-cleavedD198 →	+0.980	+2.178	.008	.035	3	3
COAD	eIF4E →	+0.279	+2.195	<.001	.034	1	5
UCEC	JNK2 →	+0.206	+2.114	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

ARHGAP30 survival (RNA) · tumor vs normal (RNA) · all ARHGAP30 data types