Across TCGA cell cohorts, ARHGAP30 mutation is significantly associated with the RNA expression of many other genes, with 832 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP30-associated genes across cancer lineages are TSPYL1, KLHL2, and OSBP. Each is linked with ARHGAP30 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP30-to-partner and partner-to-ARHGAP30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP30→partner) and Y-score (partner→ARHGAP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TSPYL1 →	+0.667	+2.364	<.001	<.001	3	3
LARGE_INTESTINE	KLHL2 →	+0.774	+2.700	<.001	.001	3	2
LARGE_INTESTINE	OSBP →	+0.534	+1.850	.002	.006	3	2
LARGE_INTESTINE	CCDC32 →	+0.447	+3.459	.001	.001	3	2
LARGE_INTESTINE	PGM3 →	+0.911	+2.364	<.001	<.001	3	2
LARGE_INTESTINE	RWDD2A →	+0.400	+2.000	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 832 associations by consensus.

Exploration

ARHGAP30 survival (RNA) · tumor vs normal (RNA) · all ARHGAP30 data types