ARHGAP28

Across TCGA patient cohorts, ARHGAP28 protein abundance is significantly associated with the RNA expression of many other genes, with 4,800 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARHGAP28-associated genes across cancer lineages are IL1R1, CNRIP1, and RECK. Each is linked with ARHGAP28 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP28-to-partner and partner-to-ARHGAP28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP28 versus IL1R1 in HNSC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP28→partner) and Y-score (partner→ARHGAP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IL1R1 →	+1.080	+0.664	<.001	.002	3	3
HNSC	CNRIP1 →	+1.014	+0.649	.002	.003	3	3
BRCA	RECK →	+0.780	+0.416	<.001	<.001	3	3
BRCA	EMILIN1 →	+0.785	+0.367	<.001	<.001	3	3
HNSC	SERPING1 →	+1.614	+0.715	<.001	<.001	3	3
BRCA	CLMP →	+0.961	+0.372	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,800 associations by consensus.

ARHGAP28 vs IL1R1 — HNSC

Explore this scatter interactively →