ARHGAP28

Across TCGA cell cohorts, ARHGAP28 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP28-associated genes across cancer lineages are COMP, CELA2A, and IL3. Each is linked with ARHGAP28 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP28-to-partner and partner-to-ARHGAP28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COMP grouped by ARHGAP28-low versus ARHGAP28-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP28→partner) and Y-score (partner→ARHGAP28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	COMP →	+0.153	+3.754	<.001	.002	3	1
BREAST	CELA2A →	+0.058	+3.758	.007	.007	3	1
BREAST	IL3 →	+0.014	+4.196	<.001	.006	3	1
BREAST	TPD52L3 →	+0.009	+4.312	<.001	.001	3	1
BREAST	FSHR →	+0.026	+4.196	<.001	.006	3	1
BREAST	OR10H5 →	+0.014	+3.963	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

COMP by ARHGAP28 expression — BLOOD_Lymphoma

Explore this box plot interactively →