ARHGAP26-IT1

Across TCGA pan-cancer cohorts, ARHGAP26-IT1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated ARHGAP26-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ARHGAP26-IT1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ARHGAP26-IT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, DLBC, and KICH are the cancer types where ARHGAP26-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.572	0.304	.003	90	view →
DLBC	OS	Tertile	II,III,IV	0.520	1.000	.003	63	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	48	view →
READ	DFS	Tertile	IV	0.223	0.709	<.001	36	view →
THYM	DFS	Tertile	III,IV	0.171	0.816	.004	27	view →
KIRP	DFS	Tertile	All	0.342	0.717	<.001	21	view →
ESCA	OS	Median	All	0.617	1.000	.009	18	view →
MESO	DFS	Tertile	All	0.168	0.502	.027	18	view →
PAAD	OS	Quartile	All	0.471	0.651	.007	18	view →
COAD	DFS	Tertile	II,III,IV	0.336	0.555	.016	11	view →
SKCM	OS	Tertile	II,III,IV	0.859	0.718	.024	9	view →
KIRC	DFS	Median	IV	0.444	0.179	.031	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

ARHGAP26-IT1–HNSC (OS)

Open the HNSC breakdown →