ARHGAP23

Across TCGA patient cohorts, ARHGAP23 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,185 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP23-associated proteins across cancer lineages are ARHGAP23_S623, TPD52, and SEC23B. Each is linked with ARHGAP23 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGAP23-to-partner and partner-to-ARHGAP23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP23 versus ARHGAP23_S623 in BRCA, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP23→partner) and Y-score (partner→ARHGAP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARHGAP23_S623 →	+0.662	+1.179	.001	<.001	3	8
BRCA	TPD52 →	-0.647	-0.842	.001	<.001	3	7
UCEC	SEC23B →	-0.355	-0.960	<.001	<.001	3	6
UCEC	ARHGAP23_S423 →	+0.839	+1.082	<.001	<.001	3	6
BRCA	MMP2 →	+0.647	+0.638	<.001	<.001	3	5
BRCA	CDH13 →	+0.701	+0.722	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,185 associations by consensus.

ARHGAP23 vs ARHGAP23_S623 — BRCA

Explore this scatter interactively →