ARHGAP23

Across TCGA patient cohorts, ARHGAP23 protein abundance is significantly associated with the RNA expression of many other genes, with 8,570 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP23-associated genes across cancer lineages are JAM3, ATF5, and PEG3. Each is linked with ARHGAP23 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP23-to-partner and partner-to-ARHGAP23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP23 versus JAM3 in CCRCC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP23→partner) and Y-score (partner→ARHGAP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	JAM3 →	+0.897	+0.657	<.001	.002	3	4
COAD	ATF5 →	-0.991	-0.725	<.001	.002	3	4
GBM	PEG3 →	+1.496	+0.416	<.001	<.001	3	4
CCRCC	GPIHBP1 →	+1.184	+0.820	<.001	.004	3	4
COAD	SERPINE1 →	-1.438	-0.617	.009	.009	3	3
COAD	CYP1B1 →	-1.493	-0.667	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,570 associations by consensus.

ARHGAP23 vs JAM3 — CCRCC

Explore this scatter interactively →