ARHGAP23

Across TCGA patient cohorts, ARHGAP23 mutation is significantly associated with the RNA expression of many other genes, with 1,941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP23-associated genes across cancer lineages are RNA5SP519, DRD5P2, and RNU6-1107P. Each is linked with ARHGAP23 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP23-to-partner and partner-to-ARHGAP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP519 grouped by ARHGAP23-low versus ARHGAP23-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP23→partner) and Y-score (partner→ARHGAP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP519 →	+0.339	+2.044	<.001	.004	3	3
LIHC	DRD5P2 →	+0.031	+5.544	<.001	.004	3	2
BRCA	RNU6-1107P →	+0.263	+5.442	<.001	.002	3	2
BRCA	RNA5SP103 →	+0.596	+4.448	<.001	.006	3	2
LIHC	SCP2D1-AS1 →	+0.055	+5.647	<.001	.004	3	2
LIHC	OR1R1P →	+0.124	+5.033	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,941 associations by consensus.

RNA5SP519 by ARHGAP23 expression — UCEC

Explore this box plot interactively →