ARHGAP23

Across TCGA cell cohorts, ARHGAP23 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,380 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ARHGAP23-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Regulation of plasma membrane repair, and Positive regulation of intracellular transport. Each is linked with ARHGAP23 in more than 12 cancer types. Because this analysis shows association rather than direction, both ARHGAP23-to-partner and partner-to-ARHGAP23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by ARHGAP23-low versus ARHGAP23-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP23→partner) and Y-score (partner→ARHGAP23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.084	+2.547	<.001	<.001	3	13
BONE	Regulation of plasma membrane repair →	+0.335	+1.332	<.001	<.001	3	13
BREAST	Positive regulation of intracellular transport →	+0.067	+2.453	<.001	<.001	3	12
BREAST	Regulation of fibroblast proliferation →	+0.118	+2.449	<.001	<.001	3	12
BREAST	Nucleic acid transport →	+0.092	+2.155	<.001	<.001	3	12
BREAST	RNA transport →	+0.092	+2.155	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,380 associations by consensus.

Small GTPase-mediated signal transduction by ARHGAP23 expression — OESOPHAGUS

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