ARHGAP22

Across TCGA patient cohorts, ARHGAP22 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,171 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP22-associated proteins across cancer lineages are PPP1R18, AIF1, and VIM. Each is linked with ARHGAP22 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGAP22-to-partner and partner-to-ARHGAP22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP22 versus PPP1R18 in UCEC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP22→partner) and Y-score (partner→ARHGAP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R18 →	+0.446	+0.604	<.001	.001	3	8
GBM	AIF1 →	+0.624	+0.702	<.001	<.001	3	8
LSCC	VIM →	+0.437	+0.604	<.001	<.001	3	8
OV	QKI →	+0.282	+0.476	<.001	<.001	3	7
OV	RIN3 →	+0.431	+0.349	<.001	.002	3	7
GBM	CD14 →	+0.837	+0.884	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,171 associations by consensus.

ARHGAP22 vs PPP1R18 — UCEC

Explore this scatter interactively →