ARHGAP22

Across TCGA patient cohorts, ARHGAP22 protein abundance is significantly associated with the RNA expression of many other genes, with 16,221 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP22-associated genes across cancer lineages are BTK, MS4A6A, and TLR7. Each is linked with ARHGAP22 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP22-to-partner and partner-to-ARHGAP22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP22 versus BTK in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP22→partner) and Y-score (partner→ARHGAP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BTK →	+1.476	+1.569	.003	.005	3	4
UCEC	MS4A6A →	+1.301	+1.473	.002	.009	3	4
UCEC	TLR7 →	+1.421	+1.473	<.001	.009	3	4
GBM	NCF4 →	+0.747	+0.373	<.001	<.001	3	3
GBM	ATP8B4 →	+0.699	+0.418	<.001	<.001	3	3
LUAD	PIK3CG →	+0.797	+0.479	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,221 associations by consensus.

ARHGAP22 vs BTK — UCEC

Explore this scatter interactively →