ARHGAP20

Across TCGA cell cohorts, ARHGAP20 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,883 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ARHGAP20-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Positive regulation of viral process, and Regulation of intracellular transport. Each is linked with ARHGAP20 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGAP20-to-partner and partner-to-ARHGAP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by ARHGAP20-low versus ARHGAP20-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP20→partner) and Y-score (partner→ARHGAP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.071	+0.568	<.001	.004	2	9
LUNG_NSCLC_LUAD	Positive regulation of viral process →	+0.060	+1.160	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Regulation of intracellular transport →	+0.046	+0.964	<.001	<.001	3	6
SOFT_TISSUE	Regulation of ubiquitin-dependent protein catabolic process →	+0.037	+0.536	<.001	<.001	3	6
SOFT_TISSUE	Golgi vesicle transport →	+0.055	+0.587	<.001	<.001	3	6
SOFT_TISSUE	Regulation of syncytium formation by plasma membrane fusion →	+0.072	+0.643	<.001	.003	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,883 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by ARHGAP20 expression — SKIN

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