ARHGAP20

Across TCGA cell cohorts, ARHGAP20 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP20-associated genes across cancer lineages are OR4M2, IL1F10, and KRT35. Each is linked with ARHGAP20 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP20-to-partner and partner-to-ARHGAP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4M2 grouped by ARHGAP20-low versus ARHGAP20-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP20→partner) and Y-score (partner→ARHGAP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR4M2 →	+0.032	+5.196	<.001	.005	3	2
BLOOD_Myeloma	IL1F10 →	+0.036	+4.807	<.001	.006	3	1
BLOOD_Myeloma	KRT35 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TLE7 →	+0.006	+4.807	<.001	.006	3	1
SKIN	DEFB129 →	+0.026	+4.437	<.001	.004	3	1
SKIN	OR10A5 →	+0.025	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

OR4M2 by ARHGAP20 expression — OVARY

Explore this box plot interactively →