ARHGAP19

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARHGAP19 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP19-associated genes across cancer lineages are INPP4B, C-Raf, and FoxM1. Each is linked with ARHGAP19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP19-to-partner and partner-to-ARHGAP19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP19→partner) and Y-score (partner→ARHGAP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.320-3.321.019.00932
UCECC-Raf →+0.175+3.459.003.00532
UCECFoxM1 →+0.228+2.906.037.00131
UCECJNK_pT183_Y185 →-0.173-1.687.015.04431
UCECJNK2 →+0.287+2.906<.001.00131
UCECKu80 →+0.239+1.713.017.02731
Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

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