ARHGAP19

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARHGAP19 mutation is significantly associated with the RNA expression of many other genes, with 211 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP19-associated genes across cancer lineages are APOL5, OR4M1, and MYF5. Each is linked with ARHGAP19 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP19-to-partner and partner-to-ARHGAP19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP19→partner) and Y-score (partner→ARHGAP19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHAPOL5 →+0.017+4.794<.001.00131
LUNG_NSCLC_LUADOR4M1 →+0.013+6.266<.001<.00131
OVARYMYF5 →+0.013+4.222<.001.00631
OVARYOR2M4 →+0.095+5.115<.001<.00131
OVARYOR2T12 →+0.049+4.339<.001.00131
OVARYOR1J2 →+0.051+3.938.007.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 211 associations by consensus.

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