ARHGAP17

Across TCGA patient cohorts, ARHGAP17 protein abundance is significantly associated with the RNA expression of many other genes, with 17,615 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP17-associated genes across cancer lineages are SIGLEC6, GINS1, and TXLNB. Each is linked with ARHGAP17 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGAP17-to-partner and partner-to-ARHGAP17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP17 versus SIGLEC6 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP17→partner) and Y-score (partner→ARHGAP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SIGLEC6 →	+0.632	+0.161	<.001	.004	3	7
LSCC	GINS1 →	-0.954	-0.231	<.001	<.001	3	7
HNSC	TXLNB →	+0.998	+0.200	<.001	<.001	3	6
LSCC	CYSLTR1 →	+0.684	+0.200	<.001	<.001	3	6
LSCC	MCM8 →	-0.648	-0.205	<.001	<.001	3	6
HNSC	GIMAP8 →	+0.946	+0.213	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,615 associations by consensus.

ARHGAP17 vs SIGLEC6 — HNSC

Explore this scatter interactively →