ARHGAP17

Across TCGA cell cohorts, ARHGAP17 mutation is significantly associated with the RNA expression of many other genes, with 642 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP17-associated genes across cancer lineages are FAM205A, DPH2, and DBT. Each is linked with ARHGAP17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP17-to-partner and partner-to-ARHGAP17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by ARHGAP17-low versus ARHGAP17-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP17→partner) and Y-score (partner→ARHGAP17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	FAM205A →	+0.024	+3.977	<.001	.006	3	2
LARGE_INTESTINE	DPH2 →	+0.541	+3.257	<.001	.002	3	2
LARGE_INTESTINE	DBT →	+0.623	+3.389	.001	.001	3	2
LARGE_INTESTINE	AMIGO1 →	+0.598	+3.628	.007	<.001	3	2
LARGE_INTESTINE	GET3 →	+0.417	+2.502	.005	.005	3	2
BLOOD_Myeloma	TAS2R1 →	+0.056	+3.716	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 642 associations by consensus.

FAM205A by ARHGAP17 expression — BLOOD_Myeloma

Explore this box plot interactively →