ARHGAP15

Across TCGA patient cohorts, ARHGAP15 protein abundance is significantly associated with the RNA expression of many other genes, with 19,056 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP15-associated genes across cancer lineages are CYTH4, GRAP2, and NCF4. Each is linked with ARHGAP15 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP15-to-partner and partner-to-ARHGAP15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP15 versus CYTH4 in GBM, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP15→partner) and Y-score (partner→ARHGAP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.075	+0.712	<.001	<.001	3	10
LSCC	GRAP2 →	+0.782	+0.477	<.001	<.001	3	10
GBM	NCF4 →	+1.195	+0.737	<.001	<.001	3	10
BRCA	CSF2RB →	+1.188	+0.547	<.001	<.001	3	10
HNSC	GZMH →	+1.402	+0.552	<.001	<.001	3	10
OV	SLA2 →	+1.110	+0.662	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,056 associations by consensus.

ARHGAP15 vs CYTH4 — GBM

Explore this scatter interactively →