ARHGAP15

Across TCGA cell cohorts, ARHGAP15 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGAP15-associated GO terms across cancer lineages are Membrane tubulation, Negative regulation of TOR signaling, and Regulation of modification of synaptic structure. Each is linked with ARHGAP15 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGAP15-to-partner and partner-to-ARHGAP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane tubulation grouped by ARHGAP15-low versus ARHGAP15-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP15→partner) and Y-score (partner→ARHGAP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Membrane tubulation →	+0.137	+2.889	<.001	<.001	3	7
LARGE_INTESTINE	Negative regulation of TOR signaling →	+0.043	+0.157	<.001	.002	3	6
LARGE_INTESTINE	Regulation of modification of synaptic structure →	+0.082	+0.136	.001	.004	3	6
BLOOD_Leukemia	Epithelial structure maintenance →	-0.148	-0.643	<.001	.005	3	5
SKIN	Internal peptidyl-lysine acetylation →	+0.134	+1.026	<.001	<.001	3	5
LARGE_INTESTINE	Microtubule organizing center organization →	+0.057	+0.155	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,882 associations by consensus.

Membrane tubulation by ARHGAP15 expression — BLOOD_Myeloma

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