ARHGAP12

Across TCGA patient cohorts, ARHGAP12 protein abundance is significantly associated with the RNA expression of many other genes, with 6,262 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ARHGAP12-associated genes across cancer lineages are ACBD5, KIF5B, and CCDC7. Each is linked with ARHGAP12 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARHGAP12-to-partner and partner-to-ARHGAP12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP12 versus ACBD5 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP12→partner) and Y-score (partner→ARHGAP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACBD5 →	+0.477	+0.289	<.001	<.001	3	8
UCEC	KIF5B →	+0.492	+0.285	<.001	<.001	3	5
GBM	CCDC7 →	+0.590	+0.357	<.001	<.001	3	5
UCEC	CCNE1 →	-1.230	-0.316	<.001	<.001	3	4
PDAC	PBLD →	+0.782	+0.249	<.001	.003	3	4
LUAD	SCP2 →	+0.416	+0.247	.005	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,262 associations by consensus.

ARHGAP12 vs ACBD5 — LSCC

Explore this scatter interactively →