ARHGAP12

Across TCGA cell cohorts, ARHGAP12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,572 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ARHGAP12-associated GO terms across cancer lineages are Phagocytosis, engulfment, Regulation of L-glutamate import across plasma membrane, and Regulation of tRNA catabolic process. Each is linked with ARHGAP12 in more than 10 cancer types. Because this analysis shows association rather than direction, both ARHGAP12-to-partner and partner-to-ARHGAP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phagocytosis, engulfment grouped by ARHGAP12-low versus ARHGAP12-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP12→partner) and Y-score (partner→ARHGAP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Phagocytosis, engulfment →	+0.126	+0.701	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of L-glutamate import across plasma membrane →	+0.185	+0.726	.004	.009	3	9
PANCREAS	Regulation of tRNA catabolic process →	-0.176	-1.123	<.001	<.001	3	8
PANCREAS	Negative regulation of tRNA catabolic process →	-0.176	-1.123	<.001	<.001	3	8
PANCREAS	Protein urmylation →	-0.070	-0.965	.001	<.001	3	8
PANCREAS	Regulation of tRNA stability →	-0.176	-1.123	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,572 associations by consensus.

Phagocytosis, engulfment by ARHGAP12 expression — PANCREAS

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