ARHGAP10

Across TCGA cell cohorts, ARHGAP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,427 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARHGAP10-associated GO terms across cancer lineages are Positive regulation of myoblast fusion, Ventricular cardiac muscle cell development, and Regulation of dendritic cell apoptotic process. Each is linked with ARHGAP10 in more than 10 cancer types. Because this analysis shows association rather than direction, both ARHGAP10-to-partner and partner-to-ARHGAP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myoblast fusion grouped by ARHGAP10-low versus ARHGAP10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP10→partner) and Y-score (partner→ARHGAP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of myoblast fusion →	+0.317	+2.649	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Ventricular cardiac muscle cell development →	+0.321	+1.978	<.001	.002	3	9
BONE	Regulation of dendritic cell apoptotic process →	+1.036	+2.213	<.001	<.001	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.198	+1.623	<.001	<.001	3	9
BONE	Cell-matrix adhesion →	+0.141	+1.700	<.001	.001	3	9
OESOPHAGUS	Activation of blood coagulation via clotting cascade →	+0.167	+0.618	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,427 associations by consensus.

Positive regulation of myoblast fusion by ARHGAP10 expression — BONE

Explore this box plot interactively →