ARGFXP1

Across TCGA pan-cancer cohorts, ARGFXP1 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated ARGFXP1 data layer.

The strongest signal is observed in thymoma (THYM), where higher ARGFXP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ARGFXP1 expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

THYM, LIHC, and KICH are the cancer types where ARGFXP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Tertile	II,III,IV	0.150	0.784	<.001	108	view →
LIHC	OS	Tertile	All	0.209	0.693	<.001	81	view →
KICH	DFS	Tertile	All	0.079	0.891	<.001	78	view →
THCA	DFS	Tertile	II,III,IV	0.694	0.894	.001	54	view →
LUSC	OS	Tertile	IV	0.001	0.673	.014	36	view →
COAD	DFS	Tertile	III,IV	0.360	0.661	.010	36	view →
MESO	OS	Tertile	IV	0.959	0.301	.021	33	view →
UCEC	OS	Tertile	All	0.340	0.750	.001	30	view →
OV	DFS	Median	IV	0.345	0.576	.006	22	view →
BLCA	OS	Tertile	III,IV	0.248	0.488	.013	18	view →
GBM	OS	Tertile	All	0.110	0.421	.006	18	view →
UCS	OS	Median	IV	0.276	0.749	.005	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

ARGFXP1–THYM (DFS)

Open the THYM breakdown →