Across TCGA patient cohorts, ARGFX mutation is significantly associated with the RNA expression of many other genes, with 442 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible ARGFX-associated genes across cancer lineages are RNU6-131P, NDUFA5P5, and RN7SL628P. Each is linked with ARGFX in more than 1 cancer types. Because this analysis shows association rather than direction, both ARGFX-to-partner and partner-to-ARGFX results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARGFX→partner) and Y-score (partner→ARGFX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-131P →	+0.236	+4.859	<.001	.004	3	2
LUAD	NDUFA5P5 →	+0.104	+4.859	<.001	.004	3	2
LUAD	RN7SL628P →	+0.223	+4.037	<.001	.004	3	2
SKCM	MTFP1 →	+0.538	+2.189	.002	.001	3	2
CESC	RNU6-1174P →	+0.338	+5.539	<.001	.004	3	2
LUSC	MIR620 →	+0.238	+5.321	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 442 associations by consensus.

Exploration

ARGFX survival (RNA) · tumor vs normal (RNA) · all ARGFX data types