Across TCGA cell cohorts, ARGFX RNA expression is significantly associated with the mutation status of many other genes, with 253 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ARGFX-associated genes across cancer lineages are TLR6, DYNC1I1, and ABCA1. Each is linked with ARGFX in more than 1 cancer types. Because this analysis shows association rather than direction, both ARGFX-to-partner and partner-to-ARGFX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARGFX→partner) and Y-score (partner→ARGFX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TLR6 →	+5.662	+0.032	.002	<.001	3	2
BLOOD_Lymphoma	DYNC1I1 →	+3.169	+0.020	.008	.001	3	2
BLOOD_Lymphoma	ABCA1 →	+3.584	+0.025	.004	<.001	3	2
CNS	OTOG →	+3.247	+0.049	.002	<.001	3	2
CNS	PER3 →	+3.832	+0.081	.005	<.001	3	2
UPPER_AERODIGESTIVE_TRACT	JAG1 →	+4.357	+0.062	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 253 associations by consensus.

Exploration

ARGFX survival (RNA) · tumor vs normal (RNA) · all ARGFX data types