ARG2

Across TCGA patient cohorts, ARG2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,869 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARG2-associated genes across cancer lineages are DOCK8, NLRC3, and SLC16A1. Each is linked with ARG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARG2-to-partner and partner-to-ARG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARG2 versus DOCK8 in HNSC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARG2→partner) and Y-score (partner→ARG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DOCK8 →	-0.766	-0.637	<.001	<.001	3	5
HNSC	NLRC3 →	-0.615	-0.716	.003	.001	3	5
UCEC	SLC16A1 →	+0.958	+0.543	.004	.001	3	4
LUAD	PRKCD →	-0.665	-1.013	.006	.006	3	4
LUAD	HLA-F →	-1.160	-1.325	<.001	.007	3	4
LSCC	ITGAL →	-0.804	-0.613	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,869 associations by consensus.

ARG2 vs DOCK8 — HNSC

Explore this scatter interactively →