ARFRP1

Across TCGA pan-cancer cohorts, ARFRP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ARFRP1 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ARFRP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ARFRP1 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, LSCC, and CCRCC are the cancer types where ARFRP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.921	.016	30	view →
LSCC	OS	Quartile	All	0.685	0.917	.009	15	view →
CCRCC	OS	Quartile	III,IV	0.336	0.834	.007	9	view →
PDAC	OS	Median	II,III,IV	0.951	0.735	.013	8	view →
LUAD	OS	Quartile	All	0.889	0.628	.019	3	view →
HNSC	DFS	Median	III,IV	0.733	0.532	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ARFRP1–COAD (DFS)

Open the COAD breakdown →