ARFRP1

Across TCGA patient cohorts, ARFRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ARFRP1-associated GO terms across cancer lineages are tRNA thio-modification, Wnt protein secretion, and Negative regulation of protein localization to chromatin. Each is linked with ARFRP1 in more than 23 cancer types. Because this analysis shows association rather than direction, both ARFRP1-to-partner and partner-to-ARFRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA thio-modification grouped by ARFRP1-low versus ARFRP1-high in KICH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFRP1→partner) and Y-score (partner→ARFRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	tRNA thio-modification →	+0.052	+0.569	<.001	<.001	2	24
TGCT	Wnt protein secretion →	+0.085	+0.605	<.001	<.001	3	18
LAML	Negative regulation of protein localization to chromatin →	+0.050	+0.328	<.001	<.001	3	17
TGCT	Galactose catabolic process →	+0.055	+0.501	<.001	<.001	3	17
DLBC	Spermidine metabolic process →	+0.055	+0.773	<.001	<.001	2	17
BRCA	Methylglyoxal metabolic process →	+0.049	+0.531	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

tRNA thio-modification by ARFRP1 expression — KICH

Explore this box plot interactively →