ARFRP1

Across TCGA cell cohorts, ARFRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ARFRP1-associated GO terms across cancer lineages are Regulation of telomeric loop disassembly, Negative regulation of t-circle formation, and GDP-mannose biosynthetic process. Each is linked with ARFRP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ARFRP1-to-partner and partner-to-ARFRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomeric loop disassembly grouped by ARFRP1-low versus ARFRP1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFRP1→partner) and Y-score (partner→ARFRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of telomeric loop disassembly →	+0.133	+0.984	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Negative regulation of t-circle formation →	+0.139	+1.578	<.001	<.001	3	15
URINARY_TRACT	GDP-mannose biosynthetic process →	+0.173	+1.022	.001	<.001	3	13
LUNG_NSCLC_LUSC	Protein depolymerization →	+0.114	+1.178	.001	.006	3	12
CNS	GDP-mannose metabolic process →	+0.117	+1.026	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of cell-substrate adhesion →	+0.104	+1.348	.004	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Regulation of telomeric loop disassembly by ARFRP1 expression — PANCREAS

Explore this box plot interactively →