ARFIP1

Across TCGA cell cohorts, ARFIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARFIP1-associated GO terms across cancer lineages are Regulation of SREBP signaling pathway, Vesicle coating, and Macroautophagy. Each is linked with ARFIP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ARFIP1-to-partner and partner-to-ARFIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of SREBP signaling pathway grouped by ARFIP1-low versus ARFIP1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFIP1→partner) and Y-score (partner→ARFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of SREBP signaling pathway →	+0.121	+0.906	<.001	.003	3	14
BLOOD_Myeloma	Vesicle coating →	+0.097	+1.037	<.001	<.001	3	13
PANCREAS	Macroautophagy →	+0.055	+0.768	<.001	<.001	3	11
BREAST	Golgi vesicle transport →	+0.077	+0.765	<.001	<.001	3	11
PANCREAS	Vesicle budding from membrane →	+0.085	+0.751	<.001	<.001	3	11
PANCREAS	DNA alkylation repair →	+0.097	+0.687	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Regulation of SREBP signaling pathway by ARFIP1 expression — OVARY

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