ARFGEF2

Across TCGA patient cohorts, ARFGEF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,103 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARFGEF2-associated proteins across cancer lineages are RTF2, TOMM34, and CSE1L. Each is linked with ARFGEF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARFGEF2-to-partner and partner-to-ARFGEF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGEF2 versus RTF2 in COAD, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGEF2→partner) and Y-score (partner→ARFGEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RTF2 →	+0.322	+0.624	<.001	<.001	3	5
COAD	TOMM34 →	+0.403	+0.546	<.001	<.001	3	5
LSCC	CSE1L →	+0.338	+0.387	<.001	<.001	3	5
COAD	STAU1 →	+0.363	+0.513	<.001	<.001	3	5
COAD	MOCS3 →	+0.440	+0.621	<.001	<.001	3	5
LSCC	XRCC1 →	+0.330	+0.425	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,103 associations by consensus.

ARFGEF2 vs RTF2 — COAD

Explore this scatter interactively →