ARFGEF2

Across TCGA cell cohorts, ARFGEF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,152 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARFGEF2-associated GO terms across cancer lineages are Endosomal transport, Vesicle-mediated transport to the plasma membrane, and Cytosolic transport. Each is linked with ARFGEF2 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARFGEF2-to-partner and partner-to-ARFGEF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by ARFGEF2-low versus ARFGEF2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGEF2→partner) and Y-score (partner→ARFGEF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Endosomal transport →	+0.055	+0.674	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.072	+0.885	<.001	<.001	3	17
STOMACH	Cytosolic transport →	+0.078	+1.070	.003	<.001	3	17
STOMACH	Golgi vesicle transport →	+0.060	+0.822	<.001	<.001	3	17
CNS	Endocytic recycling →	+0.066	+0.624	<.001	<.001	3	16
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.074	+0.772	.007	.005	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,152 associations by consensus.

Endosomal transport by ARFGEF2 expression — STOMACH

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