ARFGAP3

Across TCGA patient cohorts, ARFGAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,231 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARFGAP3-associated proteins across cancer lineages are PACSIN2, TOM1, and NF2. Each is linked with ARFGAP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARFGAP3-to-partner and partner-to-ARFGAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGAP3 versus PACSIN2 in OV, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGAP3→partner) and Y-score (partner→ARFGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PACSIN2 →	+0.458	+0.880	<.001	<.001	3	8
BRCA	TOM1 →	+0.282	+0.582	<.001	<.001	3	7
OV	NF2 →	+0.670	+0.822	<.001	.004	3	6
OV	TBC1D22A →	+0.349	+0.910	<.001	<.001	3	6
GBM	TRIOBP →	+0.271	+0.317	.005	.001	3	5
COAD	PGM3 →	+0.384	+0.630	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,231 associations by consensus.

ARFGAP3 vs PACSIN2 — OV

Explore this scatter interactively →