ARFGAP3

Across TCGA patient cohorts, ARFGAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,251 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARFGAP3-associated genes across cancer lineages are SEC24D, KDELR3, and FKBP11. Each is linked with ARFGAP3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARFGAP3-to-partner and partner-to-ARFGAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGAP3 versus SEC24D in COAD, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGAP3→partner) and Y-score (partner→ARFGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SEC24D →	+0.863	+0.353	<.001	<.001	3	8
OV	KDELR3 →	+0.881	+0.462	.003	<.001	3	8
OV	FKBP11 →	+0.784	+0.367	<.001	.001	3	6
LSCC	XBP1 →	+0.892	+0.343	<.001	<.001	3	6
UCEC	CRELD2 →	+0.919	+0.367	<.001	<.001	3	6
UCEC	GPSM2 →	-0.620	-0.312	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,251 associations by consensus.

ARFGAP3 vs SEC24D — COAD

Explore this scatter interactively →