ARFGAP3

Across TCGA cell cohorts, ARFGAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,099 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARFGAP3-associated GO terms across cancer lineages are COPI-coated vesicle budding, Golgi transport vesicle coating, and COPI coating of Golgi vesicle. Each is linked with ARFGAP3 in more than 19 cancer types. Because this analysis shows association rather than direction, both ARFGAP3-to-partner and partner-to-ARFGAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPI-coated vesicle budding grouped by ARFGAP3-low versus ARFGAP3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGAP3→partner) and Y-score (partner→ARFGAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	COPI-coated vesicle budding →	+0.142	+1.298	<.001	<.001	3	20
LIVER	Golgi transport vesicle coating →	+0.142	+1.298	<.001	<.001	3	20
LIVER	COPI coating of Golgi vesicle →	+0.142	+1.298	<.001	<.001	3	20
KIDNEY	COPII-coated vesicle cargo loading →	+0.144	+1.049	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.058	+0.667	<.001	<.001	3	15
STOMACH	Vesicle cargo loading →	+0.120	+1.040	.001	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,099 associations by consensus.

COPI-coated vesicle budding by ARFGAP3 expression — LIVER

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