ARFGAP2

Across TCGA patient cohorts, ARFGAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,261 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARFGAP2-associated genes across cancer lineages are AOC3, CR1, and PMP22. Each is linked with ARFGAP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARFGAP2-to-partner and partner-to-ARFGAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGAP2 versus AOC3 in OV, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGAP2→partner) and Y-score (partner→ARFGAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AOC3 →	-1.809	-0.299	<.001	<.001	3	6
OV	CR1 →	-0.759	-0.266	<.001	<.001	3	6
HNSC	PMP22 →	-0.840	-0.226	.002	<.001	3	5
CCRCC	F13A1 →	-1.373	-0.163	<.001	<.001	3	5
HNSC	AOC2 →	-0.767	-0.187	<.001	<.001	3	5
UCEC	MTCH2 →	+0.498	+0.205	.002	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,261 associations by consensus.

ARFGAP2 vs AOC3 — OV

Explore this scatter interactively →