ARFGAP1

Across TCGA cell cohorts, ARFGAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARFGAP1-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of organelle assembly, and Negative regulation of autophagy. Each is linked with ARFGAP1 in more than 14 cancer types. Because this analysis shows association rather than direction, both ARFGAP1-to-partner and partner-to-ARFGAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by ARFGAP1-low versus ARFGAP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGAP1→partner) and Y-score (partner→ARFGAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.064	+1.122	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of organelle assembly →	+0.074	+1.180	.001	.001	3	15
OVARY	Negative regulation of autophagy →	+0.073	+0.789	.001	<.001	3	14
KIDNEY	Positive regulation of cell morphogenesis →	+0.093	+0.950	<.001	.001	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.137	+1.131	.002	.003	3	14
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.170	+1.158	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,753 associations by consensus.

Cytosolic transport by ARFGAP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →