ARF6

Across TCGA patient cohorts, ARF6 protein abundance is significantly associated with the RNA expression of many other genes, with 9,790 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARF6-associated genes across cancer lineages are RPL36AL, TMEM170B, and LGALS3. Each is linked with ARF6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARF6-to-partner and partner-to-ARF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF6 versus RPL36AL in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF6→partner) and Y-score (partner→ARF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPL36AL →	+1.031	+0.431	.004	<.001	3	6
HNSC	TMEM170B →	-0.785	-0.462	<.001	<.001	3	6
GBM	LGALS3 →	+1.099	+0.273	<.001	<.001	3	6
UCEC	DEFB1 →	+2.276	+0.240	<.001	<.001	3	5
HNSC	NEMF →	+0.554	+0.495	<.001	<.001	3	5
HNSC	LINC01588 →	+0.569	+0.447	.002	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,790 associations by consensus.

ARF6 vs RPL36AL — HNSC

Explore this scatter interactively →