ARF5

Across TCGA patient cohorts, ARF5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,799 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARF5-associated genes across cancer lineages are GCC1, RHEB, and MKRN1. Each is linked with ARF5 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARF5-to-partner and partner-to-ARF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF5 versus GCC1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF5→partner) and Y-score (partner→ARF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GCC1 →	+0.559	+0.392	<.001	<.001	3	7
LSCC	RHEB →	+0.517	+0.218	<.001	<.001	3	6
LSCC	MKRN1 →	+0.426	+0.229	<.001	<.001	3	6
OV	METTL2B →	+0.612	+0.350	<.001	<.001	3	6
LSCC	POLR2J →	+0.525	+0.267	<.001	<.001	3	6
UCEC	BUD31 →	+0.569	+0.197	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,799 associations by consensus.

ARF5 vs GCC1 — OV

Explore this scatter interactively →