Across TCGA pan-cancer cohorts, ARF4P3 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ARF4P3’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where ARF4P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARF4P3 is over-expressed in tumor.
COAD and BRCA are the cancer types where ARF4P3 tumor–normal differential expression is most reproducible.