ARF4

Across TCGA patient cohorts, ARF4 RNA expression is significantly associated with the RNA expression of many other genes, with 19,600 significant associations in total. ACC shows the largest number of these associations.

The most reproducible ARF4-associated genes across cancer lineages are SPTY2D1, COPB2, and TMF1. Each is linked with ARF4 in more than 33 cancer types. Because this analysis shows association rather than direction, both ARF4-to-partner and partner-to-ARF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF4 versus SPTY2D1 in KICH, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF4→partner) and Y-score (partner→ARF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	SPTY2D1 →	+1.036	+0.823	<.001	<.001	3	34
UVM	COPB2 →	+1.160	+0.886	<.001	<.001	3	34
UVM	TMF1 →	+1.344	+0.774	<.001	<.001	3	34
THYM	SEC24D →	+1.541	+0.856	<.001	<.001	3	34
ACC	NUS1 →	+1.068	+1.039	<.001	<.001	3	34
UVM	TRNT1 →	+1.078	+0.777	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,600 associations by consensus.

ARF4 vs SPTY2D1 — KICH

Explore this scatter interactively →