ARF4

Across TCGA patient cohorts, ARF4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,525 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARF4-associated proteins across cancer lineages are FAM114A1, SEC24D, and P3H1. Each is linked with ARF4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARF4-to-partner and partner-to-ARF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF4 versus FAM114A1 in BRCA, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF4→partner) and Y-score (partner→ARF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM114A1 →	+0.380	+0.506	<.001	<.001	3	8
BRCA	SEC24D →	+0.371	+0.411	<.001	<.001	3	7
GBM	P3H1 →	+0.722	+0.458	<.001	.001	3	6
LUAD	SPATS2L →	+0.328	+0.296	<.001	<.001	3	6
PDAC	FN1 →	+0.824	+0.493	<.001	<.001	3	6
OV	TMF1 →	+0.345	+0.461	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,525 associations by consensus.

ARF4 vs FAM114A1 — BRCA

Explore this scatter interactively →