ARF4

Across TCGA patient cohorts, ARF4 protein abundance is significantly associated with the RNA expression of many other genes, with 18,313 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARF4-associated genes across cancer lineages are SEC24D, KDELR3, and GPX8. Each is linked with ARF4 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARF4-to-partner and partner-to-ARF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF4 versus SEC24D in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF4→partner) and Y-score (partner→ARF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEC24D →	+0.864	+0.336	<.001	<.001	3	6
LUAD	KDELR3 →	+0.923	+0.231	<.001	<.001	3	5
GBM	GPX8 →	+1.176	+0.233	<.001	.007	3	5
GBM	ANXA2 →	+1.410	+0.296	<.001	<.001	3	5
UCEC	EPHB1 →	-0.752	-0.395	<.001	<.001	3	5
BRCA	SNHG20 →	-0.570	-0.302	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,313 associations by consensus.

ARF4 vs SEC24D — BRCA

Explore this scatter interactively →