ARF4

Across TCGA patient cohorts, ARF4 protein abundance is significantly associated with the protein abundance of many other proteins, with 29,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARF4-associated proteins across cancer lineages are SAR1A, SEC13, and SEC24D. Each is linked with ARF4 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARF4-to-partner and partner-to-ARF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF4 versus SAR1A in UCEC, with a Pearson correlation of 0.55.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF4→partner) and Y-score (partner→ARF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAR1A →	+0.423	+0.435	<.001	<.001	3	8
HNSC	SEC13 →	+0.250	+0.443	<.001	<.001	3	8
LSCC	SEC24D →	+0.471	+0.423	<.001	<.001	3	8
LSCC	SEC31A →	+0.327	+0.498	<.001	<.001	3	8
PDAC	SH3BGRL3 →	+0.439	+0.433	<.001	<.001	3	8
PDAC	TMF1_T401 →	+0.610	+0.347	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,177 associations by consensus.

ARF4 vs SAR1A — UCEC

Explore this scatter interactively →