ARF1

Across TCGA cell cohorts, ARF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,341 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARF1-associated GO terms across cancer lineages are Peptidyl-arginine modification, Transcription pausing by RNA polymerase II, and Negative regulation of response to endoplasmic reticulum stress. Each is linked with ARF1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARF1-to-partner and partner-to-ARF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-arginine modification grouped by ARF1-low versus ARF1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF1→partner) and Y-score (partner→ARF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Peptidyl-arginine modification →	-0.097	-0.566	.001	<.001	3	10
LARGE_INTESTINE	Transcription pausing by RNA polymerase II →	+0.097	+0.525	.004	.008	2	10
SOFT_TISSUE	Negative regulation of response to endoplasmic reticulum stress →	+0.093	+0.561	<.001	<.001	3	9
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.117	+0.444	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	CAMP/PKA signal transduction →	+0.187	+0.699	<.001	<.001	3	9
PANCREAS	Regulation of cell cycle G1/S phase transition →	+0.055	+0.664	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,341 associations by consensus.

Peptidyl-arginine modification by ARF1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →