AREL1

Across TCGA cell cohorts, AREL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,060 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AREL1-associated GO terms across cancer lineages are RNA export from nucleus, Nucleic acid transport, and RNA transport. Each is linked with AREL1 in more than 18 cancer types. Because this analysis shows association rather than direction, both AREL1-to-partner and partner-to-AREL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by AREL1-low versus AREL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AREL1→partner) and Y-score (partner→AREL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.114	+1.029	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Nucleic acid transport →	+0.093	+1.017	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	RNA transport →	+0.093	+1.017	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.097	+0.954	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	RNA localization →	+0.090	+1.252	.002	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Microtubule nucleation →	+0.114	+1.207	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,060 associations by consensus.

RNA export from nucleus by AREL1 expression — UPPER_AERODIGESTIVE_TRACT

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