AREL1

Across TCGA cell cohorts, AREL1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AREL1-associated genes across cancer lineages are CCL1, SCRG1, and FAM205A. Each is linked with AREL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AREL1-to-partner and partner-to-AREL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL1 grouped by AREL1-low versus AREL1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AREL1→partner) and Y-score (partner→AREL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCL1 →	+0.506	+4.472	<.001	.004	3	1
LARGE_INTESTINE	SCRG1 →	+0.022	+3.793	.006	.007	1	1
LARGE_INTESTINE	FAM205A →	+0.032	+3.614	<.001	.006	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCL1 by AREL1 expression — CNS

Explore this box plot interactively →