AREG

Across TCGA patient cohorts, AREG RNA expression is significantly associated with the protein abundance of many other proteins, with 17,793 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AREG-associated proteins across cancer lineages are JUNB, MET, and PARP4_S1186. Each is linked with AREG in more than 6 cancer types. Because this analysis shows association rather than direction, both AREG-to-partner and partner-to-AREG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AREG versus JUNB in GBM, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AREG→partner) and Y-score (partner→AREG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	JUNB →	+0.415	+1.095	<.001	.001	3	7
LUAD	MET →	+0.757	+1.498	<.001	<.001	3	6
CCRCC	PARP4_S1186 →	+0.835	+1.209	.001	.004	3	6
PDAC	TNKS1BP1_S1073 →	+0.483	+0.942	<.001	<.001	3	6
LUAD	COIL_S487 →	+0.850	+1.531	<.001	<.001	3	6
LSCC	MAP7D1_S70 →	+0.553	+1.436	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,793 associations by consensus.

AREG vs JUNB — GBM

Explore this scatter interactively →