Across TCGA cell cohorts, ARC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,291 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARC-associated GO terms across cancer lineages are Nucleic acid catabolic process, Protein-RNA complex organization, and Regulation of ubiquitin-dependent protein catabolic process. Each is linked with ARC in more than 8 cancer types. Because this analysis shows association rather than direction, both ARC-to-partner and partner-to-ARC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARC→partner) and Y-score (partner→ARC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid catabolic process →	+0.052	+1.671	<.001	<.001	3	9
BONE	Protein-RNA complex organization →	+0.082	+1.886	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of ubiquitin-dependent protein catabolic process →	+0.058	+0.444	<.001	.007	2	8
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.127	+0.166	<.001	.001	3	7
BLOOD_Lymphoma	Cytoplasmic translation →	+0.064	+0.102	<.001	.003	3	7
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.125	+0.166	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,291 associations by consensus.

Exploration

ARC survival (RNA) · tumor vs normal (RNA) · all ARC data types