ARAP2

Across TCGA cell cohorts, ARAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,583 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARAP2-associated GO terms across cancer lineages are Cytoplasmic pattern recognition receptor signaling pathway, Negative regulation of actin filament bundle assembly, and Endosome organization. Each is linked with ARAP2 in more than 11 cancer types. Because this analysis shows association rather than direction, both ARAP2-to-partner and partner-to-ARAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic pattern recognition receptor signaling pathway grouped by ARAP2-low versus ARAP2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAP2→partner) and Y-score (partner→ARAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cytoplasmic pattern recognition receptor signaling pathway →	+0.072	+1.650	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of actin filament bundle assembly →	+0.119	+1.790	<.001	<.001	3	12
KIDNEY	Endosome organization →	+0.066	+1.091	.001	.001	3	11
STOMACH	Negative regulation of supramolecular fiber organization →	+0.076	+1.414	<.001	<.001	3	11
STOMACH	Negative regulation of stress fiber assembly →	+0.155	+1.411	<.001	.002	3	11
URINARY_TRACT	Retrograde protein transport, ER to cytosol →	+0.123	+1.731	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,583 associations by consensus.

Cytoplasmic pattern recognition receptor signaling pathway by ARAP2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →